Osteoporosis Among Men Treated With Androgen Deprivation for Prostate Cancer

Odense University Hospital100 enrolled

Overview

The purpose of this study is * to determine the rate of osteoporosis among patients with advanced prostate cancer. * to propose an algorithm for early detection of patients with advanced prostate cancer who are at risk of developing osteoporosis.

Patients with advanced prostate cancer are included at the initiating of androgen deprivation therapy. The patients are followed for 2 years after inclusion with blood sampling, DXA-scan, questionnaire, bone scintigraphy.

Study Type

INTERVENTIONAL

Allocation

NON_RANDOMIZED

Purpose

DIAGNOSTIC

Masking

NONE

Enrollment

100

Conditions

Prostate Cancer Androgen Deprivation Therapy Osteoporosis

Interventions

blood sampling, DXA-scan, bone scintigraphyPROCEDURE

Blood sampling 5 times DXA-scan 5 times Bone scintigraphy 3 times

Eligibility

Sex: MALE

Medical Language ↔ Plain English

Inclusion Criteria: * Prostate cancer * Initiation of androgen deprivation therapy * Oral and written informed consent Exclusion Criteria: * They withdraw their consent * Treatment for osteoporosis within the last year * Other malignancy * Other bone disease, bedbound, use of steroid

Locations (2)

Department of Urology, Odense University Hospital

Odense, Denmark

RECRUITING

Department of Urology, Roskilde Hospital

Roskilde, Denmark

RECRUITING

Outcomes

Primary Outcomes

Osteoporosis, either T-score < -2,5 or osteoporosis fracture

Time frame: 2½ years

Central Contacts

Mads H Poulsen, MD

CONTACT

Mads.Poulsen@ouh.regionsyddanmark.dk

Steen Walter, MD, DMSci, Professor

CONTACT

Data from ClinicalTrials.gov

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