Prospective Study of Cerebral Palsy Scoliosis

University of British Columbia45 enrolled

Overview

This is a prospective, multi-centre study that will be looking at two groups of males and females over the course of their operative treatment for cerebral palsy (CP) scoliosis and the years following that treatment. The first group the study will be looking at is those individuals who undergo surgery for CP Scoliosis. The second group will be those individuals who do not undergo surgical treatment for CP Scoliosis, either because the family declines surgery or surgery is not recommended during the course of study participation.

Study Type

INTERVENTIONAL

Allocation

NON_RANDOMIZED

Purpose

DIAGNOSTIC

Masking

NONE

Enrollment

Conditions

Cerebral Palsy Scoliosis

Interventions

Surgical fusionPROCEDURE

Surgical intervention for correction of scoliotic or kyphotic curvatures of the spine will include either the posterior approach or the anterior + posterior approach, with either the unit or custom rod, depending on the choice of the surgeon.

Eligibility

Sex: ALLMin age: 8 YearsMax age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Between the ages of 8 and 18 years * Diagnosis of Cerebral Palsy with total body involvement * Coronal curve greater than 40 degrees OR a kyphotic curve greater than 50 degrees on sitting film will be included * Growing rod treatment will also be included Exclusion Criteria: * Previous operated scoliotic spine deformity * Diagnosis of Rett's Syndrome * Concomitant lower extremity surgery (within 3 months of spinal fusion) * Cornelia de Lange Syndrome or any pervasive genetic disorder whose effects are due to much more than the static cortical injury * Ambulatory spastic diplegic without upper extremity impairment or speech, swallowing or other involvement

Locations (1)

BC Children's Hospital, Department of Orthopaedics

Vancouver, British Columbia, Canada

Outcomes

Primary Outcomes

Comparison of pre- and post- operative x-rays

Time frame: 1 year

Secondary Outcomes

Gross motor function, physical data, past medical history, seizure status, pain and medications, sitting ability, activity level, clinical photos, quality of life questionnaires, data regarding surgery and hospital stay

Time frame: 1 year

Data from ClinicalTrials.gov

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