Study of Blood Samples in Patients With Breast Cancer

Centre Oscar Lambret

Overview

RATIONALE: Studying the genes expressed in samples of blood from patients with cancer may help doctors identify biomarkers related to cancer. It may also help doctors predict how patients will respond to chemotherapy. PURPOSE: This clinical trial is studying blood samples in patients with breast cancer.

OBJECTIVES: * Identify constitutional gene variants associated with a change in response. OUTLINE: Blood samples are collected periodically for analysis of genetic factors.

Study Type

OBSERVATIONAL

Conditions

Breast Cancer

Interventions

laboratory biomarker analysisOTHER

Eligibility

Sex: FEMALEMin age: 18 YearsMax age: 120 Years

Medical Language ↔ Plain English

DISEASE CHARACTERISTICS: * Histologically confirmed breast carcinoma * Received first-line chemotherapy (in neoadjuvant or metastatic setting) comprising anthracyclines and/or taxanes, including for a second primary cancer * Patient agrees to conservative surgery * Hormone receptor status not specified PATIENT CHARACTERISTICS: * Menopausal status not specified * No contraindication for chemotherapy comprising anthracyclines and/or taxanes PRIOR CONCURRENT THERAPY: * See Disease Characteristics * No prior adjuvant therapy

Locations (1)

Centre Oscar Lambret

Lille, France

Outcomes

Primary Outcomes

Histologic complete response (Chevallier and Sataloff) or tumor response (RECIST)

Data from ClinicalTrials.gov

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