A Study to Demonstrate the Bioequivalence of Sitagliptin/Metformin Combination Tablets and Concomitant Administration of Sitagliptin and Metformin as Individual Tablets (0431A-048)

Inclusion Criteria: * Female subjects of reproductive potential test negative for pregnancy and agree to use appropriate contraception * Subject is in good health and is a non-smoker * Subject is willing to avoid strenuous physical activity during the study * Subject agrees to refrain from eating grapefruit or grapefruit products during the study Exclusion Criteria: * Subject has a history of neoplastic disease (cancer), stroke, chronic seizures, or major neurological disorder. Subject has a history of clinically significant endocrine, gastrointestinal, cardiovascular, hematological, hepatic, immunological, renal, respiratory, or genitourinary abnormalities or diseases * Subject consumes excessive amounts of alcohol or caffeinated beverages * Subject has donated blood, had surgery or participated in another clinical study within the past 4 weeks * Subject has a history of significant multiple and/or severe allergies to prescription or non-prescription drugs or food * Subject has a history of hypersensitivity to metformin, sitagliptin, or sitagliptin/Metformin * Subject is a regular user or past abuser of any illicit drugs * Subject is unable to refrain from or anticipates the use of any medication, including prescription and non-prescription drugs or herbal remedies during the study. * Subject is a nursing mother