Diagnostic Usefulness of Interferon Gamma Release Assay for Active Tuberculosis in Immunocompromised Patients

Yonsei University140 enrolled

Overview

For diagnosis of active tuberculosis, interferon-γ release assay based mycobacterium tuberculosis specific antigen may show higher sensitivity than tuberculin skin test in immunocompromised patients. Therefore, interferon-γ release assay have a role as a rapid diagnostic adjunctive methods for active tuberculosis in immunocompromised patients.

Study Type

OBSERVATIONAL

Enrollment

140

Conditions

Tuberculosis

Eligibility

Sex: ALLMin age: 20 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * Patient suspicious of active tuberculosis with immunocompromised condition * Immunocompromised condition patients with 1. solid cancer with chemotherapy 2. hematologic malignancy 3. organ transplantation 4. immunosuppressant 5. ESRD on renal replacement therapy 6. diabetes 7. advanced liver cirrhosis Exclusion Criteria: * Patients with 1. less than 20 years 2. who don't agree the participation of study 3. hypersensitivity history to tuberculin 4. pregnancy

Locations (1)

Yonsei Univ.

Seoul, South Korea

Data from ClinicalTrials.gov

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