RATIONALE: Studying the genes expressed in samples of tissue from patients with cancer in the laboratory may help doctors learn more about changes that occur in DNA and identify biomarkers related to cancer. It may also help doctors predict how patients will respond to treatment. PURPOSE: This research study is looking at tissue samples from patients with glioma or other brain tumors.
OBJECTIVES: Primary * To better understand the pathophysiology of gliomas and identify molecular markers that may predict prognosis and progression or that could identify new therapeutic approaches. Secondary * To compare gene expression profiles, in terms of response to treatment, and attempt to isolate subgroups of patients with objective response to certain types of chemotherapy or radiotherapy. OUTLINE: This is a multicenter study. Biological samples are collected from patients at time of surgery for diagnostic and/or treatment purposes.
Study Type
OBSERVATIONAL
Enrollment
180
laboratory biomarker analysis
pharmacogenomic studies
CHU Montpellier
Montpellier, France
Clinique Gui de Chauliac
Montpellier, France
Pathophysiology of gliomas
Pathophysiology of gliomas that may predict prognosis and progression or that could identify new therapeutic
Time frame: 1 day
Identification of molecular
Identification of molecular markers that may predict prognosis and progression or that could identify new therapeutic
Time frame: 1 day
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