A Study of Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of ABT-384 in Elderly Subjects

Inclusion Criteria: 1. Age is 65 years or greater 2. Judged to be in a condition of general good health based on the results of medical history, physical examination, vital signs, laboratory profile and a 12-lead ECG Exclusion Criteria: 1. Use of protocol-prohibited medications within 2 weeks prior to study drug administration. 2. Positive urine drug screen for non-prescribed drugs of abuse including alcohol. 3. Receipt of any drug depot by injection within 30 days prior to study drug administration. 4. Receipt of any investigational product within 6 weeks prior to study drug administration. 5. History of significant sensitivity or allergy to any drug. 6. History of drug or alcohol abuse within 2 years. 7. Positive test result for HBV, HCV or HIV. 8. Estimated creatinine clearance \< 30 mL/min. 9. Donation or loss of 5 mL/kg or more blood volume or receipt of any blood product within 8 weeks prior to study drug administration. 10. Current enrollment in another clinical study.