Adaptive Support Ventilation in the Weaning of COPD

Izmir Dr Suat Seren Chest Diseases and Surgery Education and Research Hospital97 enrolled

Overview

Adaptive support ventilation (ASV) is a closed loop ventilation mode that can act both as pressure support (PSV) and pressure controlled (PCV) ventilation. Weaning with ASV shows promising results mainly in post-cardiac surgery patients. The aim of this randomized controlled study was to test the hypothesis that weaning with ASV could reduce the weaning duration in patients with chronic obstructive pulmonary disease (COPD) when compared with PSV.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

SCREENING

Masking

SINGLE

Enrollment

Conditions

Pulmonary Disease, Chronic Obstructive

Interventions

Comparison of two different modes for weaning from mechanical ventilationPROCEDURE

Chronic obstructive pulmonary disease patients under mechanical ventilation were randomized to adaptive or pressure support ventilation modes when they met the weaning criteria.

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Diagnosis of COPD * On invasive mechanical ventilation for at least 24 hours because of hypoxemic and/or hypercapnic respiratory failure Exclusion Criteria: * Mechanical ventilation less then 24 hours (self extubation or death), * Having a tracheotomy and * COPD coexisted with severe cardiac or neurologic diseases.

Locations (1)

Izmir Dr Suat Seren Chest Diseases and Surgery Education and Research Hospital, Intensive Care Unit

Izmir, Turkey (Türkiye)

Outcomes

Primary Outcomes

Weaning duration

Secondary Outcomes

Weaning success

Length of stay in the ICU

Data from ClinicalTrials.gov

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