Pharmacokinetics and Pharmacodynamics of a Novel Pegylated Recombinant Human Granulocyte-Colony Stimulating Factor

Inclusion Criteria: * Age: Between 20 to 40 years of age, inclusive (Age based on the date to give the informed consent) * Weight: Between 60 - 75 kg, within ±20% of ideal body weight * Normal clinical laboratory findings, especially for ANC value between 2000 to 7500, inclusive * Subject who are reliable and willing to make themselves available during the study period, are willing to follow the study protocol, and give their written informed consent voluntarily Exclusion Criteria: * History of hypersensitive reaction to medication (aspirin, antibiotics) * History of significant clinical illness needs medical caution, including cardiovascular, immunologic, hematologic, neuropsychiatric, respiratory, gastrointestinal, hepatic, or renal disease or other chronic disease * History or evidence of drug abuse * Use any prescriptive medication, Korean traditional medication not considered acceptable by the clinical investigator during the last 14 days period before first dosing, or use any OTC medication not considered acceptable by the clinical investigator during the last 7 days period before first dosing (if used medication is considered acceptable by investigator, patients can be included) * Participation in clinical trials of any drug within 60 days prior to the participation of the study * Donation of whole blood within 60 days or a unit of blood within 30 days prior to the start of study * Judged to be inappropriate for the study by the investigator