The Phase Ia, open-label, multicenter study will consist of a single-dose, dose-escalation study of the safety, tolerability, pharmacokinetics, and immunogenicity of an intravitreal (ITV) injection of FCFD4514S in patients with Geographic Atrophy (GA).
Study Type
INTERVENTIONAL
Allocation
NA
Purpose
TREATMENT
Masking
NONE
Enrollment
18
Intravitreal escalating dose
Safety and tolerability of the study drug
Time frame: Through study completion or early study discontinuation
PK parameters of study drug (total exposure, maximum observed serum concentration, and time of maximum observed serum concentration)
Time frame: Through study completion or early study discontinuation
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