Psychophysiological Correlates of Mindfulness Based Cognitive Therapy (MBCT) in Recurrent Depression

University Hospital Tuebingen120 enrolled

Overview

The study investigates cognitive attention, rumination and psychophysiological (EEG) processes in healthy subjects and remitted patients with at least three previous depressive episodes. The investigators expect that Mindfulness Based Cognitive Therapy prevents future depressive episodes and has influence on cognitive and psychophysiological measures.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

SINGLE

Enrollment

120

Conditions

Depression

Interventions

Mindfulness Based Cognitive TherapyBEHAVIORAL

Group treatment over 8 weeks with training in meditation, stress regulation, shift attention, stay present, in addition with cognitive and behavioral strategies (following Williams et al. Manual 2002)

Waiting List ControlOTHER

Patients receive MBCT with a delay of 6 months.

Eligibility

Sex: ALLMin age: 18 YearsMax age: 65 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * recurrent depression with at least 3 previous MD-episodes, currently remitted (no symptoms) Exclusion Criteria: * current depression * lifetime schizophrenia * bipolar or schizoaffective disorder * any neurological disorders * other psychopathology during last 3 years

Locations (1)

Department of Psychology University of Tuebingen

Tübingen, Germany

Outcomes

Primary Outcomes

Relapse (MDE)

Time frame: 12 month

Secondary Outcomes

Electroencephalography (EEG)

Time frame: 6 month

Data from ClinicalTrials.gov

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