Endostar Combined With CHOP Regimen as First Line Chemotherapy for Peripheral T Cell Lymphoma

Inclusion Criteria: * Disease Characteristics: * Diagnosis of peripheral T-cell: * Any stage disease allowed * At least 1 objective measurable disease parameter * No anaplastic lymphoma kinase (ALK)-positive T-cell large cell lymphoma * ALK-negative T-cell large cell lymphoma allowed * No cutaneous T-cell lymphoma * No sezary syndrome * No NK/T cell lymphoma * No history of or current radiographic evidence of CNS metastasis, including previously treated, resected, or asymptomatic brain lesions or leptomeningeal involvement * Patient Characteristics: * Age: * 18 -75 years * Performance status: * ECOG 0-2 * Life expectancy: * No less than 12 weeks * Hematopoietic: * Absolute neutrophil count ≥ 1,500/mm\^3 * Hemoglobulin ≥ 80\*10\^12/L * Platelet count ≥ 100,000/mm\^3 * No evidence of bleeding diathesis or coagulopathy * Hepatic: * Bilirubin ≤ 1.5 mg/dL * AST ≤ 2.5 times ULN * PT, INR, and PTT ≤ 1.5 times normal * Renal: * Creatinine ≤ 1.5 times normal * Cardiovascular: * No cerebrovascular accident within the past 6 months * No myocardial infarction within the past 6 months * No unstable angina within the past 6 months * No New York Heart Association class II-IV congestive heart failure * No uncontrolled hypertension (i.e., systolic blood pressure \[BP\] \> 150 mm Hg or diastolic BP \> 100 mm Hg) * No other clinically significant cardiovascular or peripheral vascular disease * LVEF is normal * Other: * Not pregnant or nursing * Fertile patients must use effective contraception * No history of active seizures * No non-healing ulcer (unless involved with lymphoma) * No active infection requiring parenteral antibiotics * No known HIV positivity * No other active malignancy within the past 6 months except carcinoma in situ of the cervix or basal cell carcinoma of the skin * PRIOR CONCURRENT THERAPY: * Biologic therapy: * Not specified * Chemotherapy: * No prior chemotherapy was allowed * Surgery: * More than 4 weeks since prior major invasive surgery or open biopsy * At least 7 days since prior minor surgery * No concurrent major surgery Exclusion Criteria: * Prior treatment included chemotherapy and radiotherapy * With the following risk factors: Uncontrolled or severe cardiovascular disease (e.g., myocardial infarction within the past 6 months, congestive heart failure treated with medications, or uncontrolled hypertension) * Pregnant or nursing * Other currently active malignancy except nonmelanoma skin cancer * Uncontrolled or severe bleeding,diarrhea,intestinal obstruction * Hypersensitivity to albumen