Muscle Glycogen Synthesis When Caffeine and Protein is Co-Ingested With Carbohydrates

Maastricht University Medical Center14 enrolled

Overview

The aim of the present study is to investigate the effect of added protein+leucine or caffeine to 1.2 g/kg/h CHO on the rate of post-exercise muscle glycogen re-synthesis in healthy, recreational athletes. The investigators hypothesize that both interventions (the addition of caffeine or protein+leucine) will lead to higher glycogen re-synthesis compared to the ingestion of CHO only, and that the co-ingestion of protein and leucine will result in the highest muscle glycogen synthesis rates.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

BASIC_SCIENCE

Masking

DOUBLE

Enrollment

Conditions

Exercise Recovery

Interventions

CarbohydrateDIETARY_SUPPLEMENT

1.2 g/kg/h

Carbohydrate and protein ingestionDIETARY_SUPPLEMENT

1.2 g/kg/h carbohydrate plus 0.4 g/kg/h protein

Carbohydrate and caffeine ingestionDIETARY_SUPPLEMENT

1.2 g/kg/h carbohydrate and 1.67 g/kg/h caffeine

Eligibility

Sex: MALEMin age: 18 YearsMax age: 35 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * male cyclists * healthy * BMI \< 25 Exclusion Criteria: * female * use of medication * non cycling * BMI \> 25

Locations (1)

Maastricht University

Maastricht, Netherlands

Outcomes

Primary Outcomes

Muscle glycogen synthesis rates

Time frame: 6 hours

Secondary Outcomes

Glycogen synthase activity, plasma glucose, insulin, free fatty acids and epinephrine responses

Time frame: 6 hours

Data from ClinicalTrials.gov

This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.