Carotid Ultrasound Sub-Study of the Familial Atherosclerosis Study-observational Study

University of Washington76 enrolled

Overview

This observational study looks at Carotid Stenosis in two groups of subjects using a non-invasive procedure, B-mode ultrasound. One group of subjects has had long-term intensive lipid altering therapy (lowering LDL-C plus raising HDL-C). The second group of patients has been on conventional "standard of care" treatment for carotid stenosis. The study will look at the Carotid Intima-media Thickness (CMIT) in both groups. Hypothesis: CIMT will differ between the two groups, such that the CIMT will be less in the subjects on intensive lipid altering therapy.

Study Type

OBSERVATIONAL

Enrollment

Conditions

Carotid Stenosis

Eligibility

Sex: MALE

Medical Language ↔ Plain English

Inclusion Criteria: * Intensive Lipid-lowering Therapy Group: Subjects currently enrolled in the Familial Atherosclerosis Treatment Observational Study. * Usual Care Group: Subjects who were in the FATS OS Study in the past, but have since quit the study and opted for conventional "standard of treatment". Exclusion Criteria: * No past or present participation in the FATS OS Study.

Locations (1)

University of Washington

Seattle, Washington, United States

Outcomes

Primary Outcomes

Carotid Intima-media Thickness

Time frame: Up to 3 years

Data from ClinicalTrials.gov

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