The aim of this trial is to evaluate the safety and virological and immunological efficacy of Aptivus in treatment-experienced patients with advanced HIV-1 infection who had developed resistance to more than one protease inhibitor.
Study Type
OBSERVATIONAL
Enrollment
42
low-dose
Boehringer Ingelheim Investigational site 9
Arad, Romania
Boehringer Ingelheim Investigational site 13
Bacau, Romania
Number of Patients Reporting Adverse Events (AE)
Any type of adverse events
Time frame: 48 weeks
Virologic Response
Virologic response is defined as HIV viral load of \< 50 copies/mL before week 48 and without subsequent rebound or change of ARV therapy prior to week 48. A rebound is defined by two consecutive measurements of VL \>= 50 copies/ml, at least two weeks apart, after two consecutive measurements of VL\< 50 copies/ml. Because of many missing data concerning the viral load, the virologic response could be determined only for four patients.
Time frame: 48 weeks
Change in CD4+ Cell Count From Baseline at Week 48
Time frame: 48 weeks
This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.
Boehringer Ingelheim Investigational site 17
Brasov, Romania
Boehringer Ingelheim Investigational site 18
Brasov, Romania
Boehringer Ingelheim Investigational site 19
Brasov, Romania
Boehringer Ingelheim Investigational site 1
Bucharest, Romania
Boehringer Ingelheim Investigational site 2
Bucharest, Romania
Boehringer Ingelheim Investigational site 3
Bucharest, Romania
Boehringer Ingelheim Investigational site 4
Bucharest, Romania
Boehringer Ingelheim Investigational site 5
Bucharest, Romania
...and 10 more locations