Peripheral Optics in Myopia and Orthokeratology

The Hong Kong Polytechnic University90 enrolled

Overview

The primary objective of the current study is to investigate changes in peripheral refraction and aberration in children wearing orthokeratology lenses and single-vision spectacles.

Apart from being effective in reducing low to moderate myopia, orthokeratology has been shown to have potential in retarding myopic progression. The central cornea is flattened and peripheral optics altered in orthokeratology and it has been suggested that orthokeratology slows myopic progression through the alteration of peripheral optics. The aim of the current study is to investigate the changes in peripheral refraction and aberration in children wearing orthokeratology (study group) and single-vision spectacles (control group).

Study Type

INTERVENTIONAL

Allocation

NON_RANDOMIZED

Purpose

TREATMENT

Masking

NONE

Enrollment

Conditions

Myopia

Interventions

Orthokeratology lensesDEVICE

Nightly use of orthokeratology lenses to correct the refractive errors

SpectaclesDEVICE

Daily use of single vision lenses to correct refractive errors

Eligibility

Sex: ALLMin age: 6 YearsMax age: 9 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * Myopia (refractive sphere): \> 0.50D and ≤ 6.00D * Astigmatism: with-the-rule astigmatism (axes 180 +/- 30) ≤ 1.50D; astigmatism of other axes ≤ 0.50D * Spherical equivalent (SE): \> 0.50D and ≤ 6.75D (myopia) * Best corrected monocular visual acuity: equal to or better than 6/7.5 in Snellen scale * Willingness to wear contact lenses or spectacles on a daily basis * Availability for follow-up for at least 2 years Exclusion Criteria: * Strabismus at distance or near * Contraindication for contact lens wear and orthokeratology (e.g. limbus to limbus corneal cylinder and dislocated corneal apex) * Prior experience with the use of rigid lenses (including orthokeratology) * Prior experience with myopic control treatment (e.g. refractive therapy or progressive spectacles) * Systemic or ocular conditions which may affect contact lens wear (e.g. allergy and medication) * Systemic or ocular conditions which may affect refractive development (e.g. Down syndrome, ptosis)

Locations (1)

School of Optometry, The Hong Kong Polytechnic University

Hong Kong, Hong Kong, China

Outcomes

Primary Outcomes

Changes in cycloplegic off-axial auto-refraction, aberration and eyeball length

Time frame: 2 years

Data from ClinicalTrials.gov

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