The Time of Positive Conversion of Interferon-γ Releasing Assay After Tuberculosis Exposure

Armed Forces Capital Hospital, Republic of Korea32 enrolled

Overview

The aim is to evaluate the time of positive conversion after exposure to smear positive pulmonary tuberculosis (TB) in a platoon of Korean military, a closed communal setting.

In a platoon where TB outbreak occurred, we performed low dose chest CT (LDCT), QuantiFERON-TB gold in tube (QFT) and two-step (0, 4weeks) TST for outbreak investigation. We perform QFT at 0, 2, 4, 8 and 12 weeks after initial investigation for soldiers with negative QFT results, and soldiers with positive QFT and normal LDCT took isoniazid and rifampin for 3 months as treatment of latent TB.

Study Type

OBSERVATIONAL

Enrollment

Conditions

Tuberculosis

Eligibility

Sex: MALEHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * All soldiers who assigned to the military platoon where a tuberculosis outbreak occurred Exclusion Criteria: * Soldiers who could not complete study or refused the study protocol

Data from ClinicalTrials.gov

This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.