Search for Biomarkers in Human Glaucoma: Lymphocytes Alterations and Rate of Progression

University of Parma40 enrolled

Overview

The aim of this study was to evaluate the lymphocyte phenotype in primary open- angle glaucoma (POAG) patients compared to healthy subjects of the same age, in order to confirm the importance of immune responses in glaucoma and the possible correlation to the severity of the disease.

Study Type

OBSERVATIONAL

Enrollment

Conditions

Glaucoma, Open-Angle

Eligibility

Sex: ALLMin age: 19 YearsMax age: 85 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Clinical diagnosis of primary open-angle glaucoma * age between 19 an 85 years old Exclusion Criteria: * age less than 19 or more than 85 yrs * positive history for (a) neurodegenerative diseases, (b) autoimmune diseases, (c) cancer, (d) viral infection and (e) diabetes, (f)systemic inflammation

Locations (1)

Azienda ospedaliera universitaria

Parma, Italy

Outcomes

Primary Outcomes

compare the lymphocyte phenotype of POAG patients to healthy subjects of the same age

Time frame: the same day of bloodwithdrawal

Secondary Outcomes

correlate the immunophenotype of POAG patients to the severity of disease

Time frame: within 3 months after blood withdrawal

Data from ClinicalTrials.gov

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