The Effect of Late Night Meals on Fasting Glucose in Type 2 Diabetes Patients

Sheba Medical Center19 enrolled

Overview

High fasting glucose is a very common problem in type 2 diabetic patients. The cause is probably glucose production by the liver, known as the "dawn phenomenon". The investigators hypothesize that a late night meal can lower the fasting glucose level by early morning insulin secretion stimulated by the food. In this study the investigators intend to test the effect of different kinds of late night meals on fasting glucose in type 2 diabetic patients.

Study Type

INTERVENTIONAL

Allocation

Purpose

TREATMENT

Masking

NONE

Enrollment

Conditions

Fasting Hyperglycemia

Interventions

late night mealDIETARY_SUPPLEMENT

Three different kinds of late night meal each for 2 days.

Eligibility

Sex: ALLMin age: 30 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Type 2 diabetes mellitus with HbA1c 6.5-9%, fasting glucose of 126-200 mg/dl and BMI of 27-40. Exclusion Criteria: * Patient treated with insulin, GLP-1 analog or weight reduction medications. * Type 1 diabetes * Pregnancy * Renal failure (creatinin \>1.4 for male and 1.3 for female * Uncontrolled hypertension (\>160/100) * Abnormal thyroid function test * Patient treated with steroids or psychiatric medications.

Outcomes

Primary Outcomes

fasting glucose level

Time frame: 2 weeks

Data from ClinicalTrials.gov

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