Alcohol Cessation Intervention in an Acute Surgical Setting

Inclusion Criteria: * Drinking 21 or more drinks(one drink containing 12 g ethanol) per week for at least 3 months * Traumatic ankle fracture requiring internal fixation (osteosynthesis; more than just Kirschner threads or similar minor intervention) * Informed consent * Randomisation within 36 hours after entering the orthopaedic department Exclusion Criteria: * Major trauma involving other fractures or major lesions, * Preoperative severe psychiatric disorders (including medicine addiction, severe alcohol dependence \[defined as experience of delirium or seizures during abstinence from alcohol\], dementia) or other conditions of reduced ability for giving informed consent * Pathological fractures * Pregnancy and lactation * Allergy to benzodiazepines, anaesthesia, pain treatment or disulfiram * Uncompensated chronic diseases (including fulminate cardiac or liver insufficiency, which are contraindications for disulfiram) * ASA score 4-5 * Canceled operation * Withdrawal of informed consent