The goal of this study is to generate pilot data exploring the addition of an augmentation (additional) medication to patients suffering from bulimia nervosa who have responded but not had complete symptom resolution with a course of standard medication treatment.
The aim of this study is to determine whether the addition of an augmentation medication (topiramate 200mg/d) will confer additional reductions in symptomatology in BN patients who have received six weeks of standard pharmacological treatment with fluoxetine 60 mg/day or its equivalent and had a partial response but are not in symptomatic remission.
Study Type
INTERVENTIONAL
Allocation
NA
Purpose
TREATMENT
Masking
NONE
Topiramate titrated to 200mg/day over four weeks, for ten weeks
Neuropsychiatric Research Institute (NRI)
Fargo, North Dakota, United States
Weekly number of binge eating episodes and purging episodes
Time frame: Weekly for 10 weeks
Abstinence from BN symptoms
Time frame: Baseline and endpoint (week 1 and week 10)
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