The purpose of this study is to determine whether memantine will enhance the therapeutic of effect on depression and prevent memory and other cognitive problems caused by ECT.
Patients will be assigned randomly either to a treatment group or a placebo groups. All patients in both groups will be receiving standard ECT. The treatment group will receive memantine. All patients will be given a battery of cognitive tests and test of depression before ECT treatments start, after the 6th ECT treatment and after the completions of ECT. An analysis will be performed to see if memantine causes any impact on the response to ECT and prevents memory and cognitive impairment.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
QUADRUPLE
University of Iowa hosptitals and clinic
Iowa City, Iowa, United States
Assessment of whether Memantine protects memory and cognitive impairment caused by ECT.
Time frame: 6 to 8 weeks
Whether memantine will improve response of Depression to Electroconvulsive therapy.
Time frame: 6-8 weeks
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