The purpose of this study is to attenuate the systemic inflammatory response after Endovascular repair of abdominal aortic aneurysms, by administration of a single preoperative dosage of Methylprednisolone.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
QUADRUPLE
Enrollment
150
A single preoperative dosage 30 mg/kg Methylprednisolone suspended in physiological saline (100 ml in total) given intravenously as a 30 minute infusion, 2 hours before surgery.
A single preoperative dosage 100 ml given intravenously as a 30 minute infusion, 2 hours before surgery
Department of Vascular Surgery, Rigshospitalet 3111
Copenhagen, Denmark
Systemic inflammatory response syndrome - SIRS
Time frame: Within 5 postoperative days
Length of postoperative hospital stay
Time frame: Until discharge
Interleukin 6 plasma level
Time frame: Within 5 postoperative days
Adverse events related to Methylprednisolone
Time frame: Within 5 postoperative days
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