Safety and Pharmacokinetics of Ascending Single Oral Doses of EDP-322 in Nonfasting and Fasting Healthy Volunteers

Inclusion Criteria: * Healthy adult males or females \[if documentation existed that they were surgically sterilized\]. * Were in good general health as determined by medical history, physical exam and clinical laboratory tests, and without evidence of clinically significant abnormality, in the opinion of the Investigator and Medical Monitor. * The resting 12-lead ECG obtained at Screening shows no clinically significant abnormality and a QTc (Bazett's correction) \<450 msec. * Weight less than 132 pounds (60kg) with BMI between 18-32 kg/m3, inclusive. * Subject has read, understood, and signed the written informed consent form. Exclusion Criteria: * History of chronic or recurrent renal, hepatic, pulmonary, allergic, cardiovascular, gastrointestinal, endocrine, central nervous system, hematologic or metabolic diseases, or immunologic, emotional and/or psychiatric disturbances. * History of gastric surgery, vagotomy, bowel resection, or any surgical procedure that might interfere with gastrointestinal motility, pH, or absorption. * Any abnormal or screening clinical lab test results... * Medication Related exclusions... * Lifestyle related...