Autologous cultured adipocytes (ANTG-adip) is produced by well-established techniques including cell harvesting from lipoaspirates, expansion of adipose tissue derived stem cells, and differentiation into pure and immature adipocytes. This was an open-label, dose-escalation study. Patients are given subcutaneous injection of ANTG-adip and followed for 12 weeks according to the clinical trial protocol.
Study Type
INTERVENTIONAL
Allocation
NA
Purpose
TREATMENT
Masking
NONE
Enrollment
36
autologous cultured adipocytes (ANTG-adip)
Samsung Medical Center
Seoul, South Korea
Efficacy: recovery rate(%)
Time frame: week 12
Safety: clinically measured abnormality of laboratory tests and adverse events, Injection site observation, Immune rejection test
Recovery rate (%)
Time frame: day 7, 14, 21, 28 days and week 8
A digital photograph
Time frame: day 1, 3, 7, 14, 21, 28, week 8 and week 12
Patient satisfaction
Time frame: week 12
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