In this study the investigators will evaluate the effect of both low and high frequency Deep Brain stimulation of the subthalamic nucleus (STN) in Parkinson's patients who have noted a change in their walking. The investigators' hypothesis is: 1. Stimulation at 60 Hertz (Hz) is associated with improved gait with increased stride length and faster time on the Stand walk sit test. 2. There is no worsening of the Unified Parkinson's Disease Rating Scale (UPDRS) at 60 Hz.
Study Type
INTERVENTIONAL
Allocation
NA
Purpose
TREATMENT
Masking
DOUBLE
Enrollment
20
60 Hz stimulation for one hour, done twice over the 5 hour study period in a randomized blinded fashion.
130 Hz Stimulation for one hour, done twice over the 5 hour study period in a randomized blinded fashion.
Vanderbilt University
Nashville, Tennessee, United States
Change in Stride Length From Baseline
Evaluation performed after DBS frequency setting changed for one hour, compared to the subject's baseline DBS frequency stride length
Time frame: 1 hour
Gait Velocity
gait velocity measured as change from baseline in in CM/second
Time frame: 5 hours
Time to Walk 14 Meters
Change in the time to walk 14 meters compared to baseline measured in seconds
Time frame: 5 hours
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