Biomarkers for Bipolar Disorder: Chaperones and Reticulum Endoplasmatic Stress Response CHAP´s Study

University of Sao Paulo20 enrolled

Overview

The purpose of this study is to determine expression of chaperones proteins from the endoplasmatic reticulum stress response system in bipolar I patients (manic phase) compared to healthy controls. Hypothesis: There is no difference in chaperones proteins expression between bipolar I manic patients and healthy controls

Study Type

OBSERVATIONAL

Enrollment

Conditions

Bipolar Disease Type I

Eligibility

Sex: ALLMin age: 18 YearsMax age: 55 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * Bipolar Disease type I manic phase * YMRS \> 14 * HDRS \< 9 Exclusion Criteria: * Use of lithium, divalproate, or carbamazepine in therapeutic levels over the past 30 days

Locations (1)

Mood Disorders Program, Institute of Psychiatry, Faculty of Medicine, University of Sao Paulo

São Paulo, São Paulo, Brazil

Data from ClinicalTrials.gov

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