Rationales for Wound Care Management in Old World Cutaneous Leishmaniasis Patients

Inclusion Criteria: 1. Present a suspected Old World Cutaneous Leishmaniasis lesion confirmed by Giemsa stained wound smears with no other skin diseases or infections and who 2. Have never been previously treated with antimonial injections or any other form of anti-leishmanial medication. Exclusion Criteria: 1. Patients with more than one lesion are excluded. 2. Patients with a lesion age of \> 3 months are also excluded. The experience of the Kabul trial shows that patients presenting themselves for the first time with a lesion, which is older than three months, have either been pre-treated somewhere else and/or show a poor compliance during the trial. 3. Patients below 12 years of age have to be excluded from the trial, because they cannot fill in the EQ-5D and Skindex questionnaire part of the health economic evaluation. 4. Intralesional antimony injections are too painful for lesions located on the nose, lips or eyes. Therefore, patients presenting these lesions are excluded from the trial. 5. For compliance reasons addicted patients and patients not available for follow-up are exclude from the trial. 6. Patients with major uncontrolled diseases as tuberculosis, diabetes or HIV are excluded from the trial, since their management requires additional co-medications, which may affect wound healing.