Staphylococcus aureus, a bacteria that lives commonly in the anterior nostrils, is seen in about 30% of healthcare workers. Applying mupirocin ointment, a prescription, to the nostrils twice daily for 5 days is the current standard of care for treatment to clear this bacteria. This research study is designed to determine the rate of clearance of this bacteria in healthcare workers who are carriers when using triple antibiotic ointment instead of mupirocin ointment.
Study Type
INTERVENTIONAL
Allocation
NA
Purpose
TREATMENT
Masking
NONE
Enrollment
216
2 1/32oz packages will be dispensed. If positive nasal swab for S. aureus, subjects will apply a small amount to anterior nares twice daily for 5 days.
Northwestern University
Chicago, Illinois, United States
Carrier Rate for Staphylococcus Aureus
Percentage of subjects with baseline culture positive for Staphylococcus aureus (via nasal swab)
Time frame: Baseline
MSSA Clearance Rate
Percentage of subjects with methicillin-sensitive S. aureus on Baseline culture who achieved clearance with treatment.
Time frame: 14 days
MRSA Clearance Rate
Percentage of subjects with methicillin-resistant S. aureus on Baseline culture who achieved clearance with treatment.
Time frame: 14 days
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