The purpose of this study is to evaluate changes in adrenal hormones during adrenal radiofrequency (RF) ablation.
Adrenal radiofrequency (RF) ablation has been increasingly used for the treatment of unresectable adrenal tumors. But one of the major complication is a increase in blood pressure. Hormonal release during RF ablation is considered the cause of hypertension. But there has been no evidence that adrenal hormones affects changes in blood pressure. In this prospective study, we evaluate the changes in adrenal hormones during RF ablation and clarify the cause of hypertensive crisis.
Study Type
INTERVENTIONAL
Allocation
NON_RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Enrollment
18
Radiofrequency (RF) ablation was done after RF electrodes were placed in the adrenal tumor in the adrenal RF ablation group. RF ablation was done after RF electrodes were placed in the targeted abdominal tumors other than adrenal gland in the abdominal RF ablation other than adrenal gland group.
Mie University Hospital
Tsu, Mie-ken, Japan
Mie University
Tsu, Mie-ken, Japan
Increase in Catecholamine
Time frame: One day
Serum Cathecholamine Levels
Time frame: around one year
Number of Participants With Hypertension During Adrenal or Non-adrenal Radiofrequency Ablation
Blood pressure was monitored during radiofrequency (RF) ablation. The frequency of hypertension (systolic blood pressure of more than 200 mmHg) was evaluated and compared between the adrenal and non-adrenal (RF ablation other than adrenal gland) RF ablation groups.
Time frame: 1 week
Increase in Cortisol
Time frame: 1 day
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