Randomized Trial of Alerts in Patients Demonstrating a "Triple Low"

The Cleveland Clinic9,846 enrolled

Overview

The investigators propose to test the theory that smart alarms for the Triple Low State incorporated into a decision support system built into an electronic anesthesia record will prompt clinicians to intervene earlier in situations that would otherwise provoke little concern, and that the alert system will reduce 90-day mortality. Specifically, the investigators will test the hypothesis that providing Triple Low alerts reduces 90-day mortality.

Study Type

OBSERVATIONAL

Enrollment

9,846

Conditions

Low Bispectral Index Low Mean Arterial Blood Pressure Low End-tidal Anesthetic Concentration

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Adults presenting for non-cardiac surgery under volatile general anesthesia

Locations (1)

Cleveland Clinic

Cleveland, Ohio, United States

Outcomes

Primary Outcomes

90-day mortality

Time frame: 90-days

Secondary Outcomes

30-day mortality

Time frame: 30-days

Response to alerts

Vasopressor administration within 5 minutes or reduction in volatile anesthetic within 15 minutes of Triple Low onset

Time frame: Intraoperative

Hospital-free days within the initial postoperative month

Time frame: 30-days

Data from ClinicalTrials.gov

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