Assess the Effect of Erythromycin on the Rate of Success in Placement of a Self-propelled Feeding Tube

Canisius-Wilhelmina Hospital

Overview

The purpose of this study is to assess the effect of erythromycin on the Rate of Success in Placement of a Self-propelled Feeding Tube.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

QUADRUPLE

Conditions

Pancreatitis

Interventions

ErythromycinDRUG

Subjects receive 4x250mg erythromycin i.v. daily after intubation of a self-propelled feeding tube

PlaceboDRUG

Subjects receive 4x placebo i.v. daily after intubation of a self-propelled feeding tube

Eligibility

Sex: ALLMin age: 18 YearsMax age: 80 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Aged 18-80 years * Having pancreatitis * Require jejunal enteral nutrition Exclusion Criteria: * Known impaired peristalsis (critically ill patients, postoperative patients, history of surgery of the stomach/duodenum) * Pregnancy * Hypersensibility to erythromycin * Cardiac arrhythmias with a prolonged QT-time * Simultaneous usage of drugs impairing peristalsis

Outcomes

Primary Outcomes

The success rate of spontaneous positioning the tubes tip into the jejunum, beyond Treitz ligament, after 48 hours.

Secondary Outcomes

The success rate of spontaneous positioning the tubes tip into the jejunum, beyond Treitz ligament, after 24 hours.

Adverse events using this self-propelled tube

Data from ClinicalTrials.gov

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