Study on the Effect of Mitomycin C 0.02% on the Corneal Endothelial After Photorefractive Keratectomy in Moderate Myopia

Shahid Beheshti University of Medical Sciences

Overview

In this study 126 eyes in 63 patients with moderate bilateral myopia and astigmatism between -3 and -5 (SE difference between two eyes should not be more than 0.75 and the residual corneal thickness\>350 μ ) were entered in the study. One eye went randomly under PRK with mitomycin C 0.02% in 15 min and then the other eye went under the operation without MMC. UCVA,BCVA, refractory error after the operation and the number of endothelial cells before and after the surgery would be compared in 6 months.

Study Type

INTERVENTIONAL

Conditions

Myopia

Interventions

Mitomycin C 0.02%DRUG

PlaceboDRUG

Eligibility

Sex: ALLMin age: 19 YearsMax age: 60 Years

Medical Language ↔ Plain English

Inclusion Criteria: * 19 \< age \< 60 * Refractory error stabled for at least one year * No corneal pathology * -3 \< bilateral myopia and astigmatism \< -5 with no difference more than 0.75 between 2 eyes Exclusion criteria: * Keratoconus * Ectatic corneal disease * Glaucoma * Corneal dystrophy * Lens changes affecting the visual acuity * Anterior or posterior uveitis * Corneal scar

Locations (1)

Ophthalmic Research Center

Tehran, Iran

RECRUITING

Central Contacts

Mohammad Ali Javadi, MD

CONTACT

+982122585952 labbafi@hotmail.com

Data from ClinicalTrials.gov

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