The investigators will test whether an intravenous infusion of saline (salt water) will improve the exercise capacity in patients with postural tachycardia syndrome (POTS).
Study Type
INTERVENTIONAL
Allocation
NON_RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Enrollment
40
Vanderbilt University
Nashville, Tennessee, United States
Difference in VO2max between saline day and placebo day
VO2max will be measured hours after saline and after placebo. The 2 interventions will be less than 2 weeks apart.
Time frame: Within 2 week
Exercise capacity/Maximal Load (Watts) during peak VO2
Maximal exercise load will be measured hours after saline and after placebo. The 2 interventions will be less than 2 weeks apart.
Time frame: Less than 2 weeks
Cardiac output between exercise tests (inert gas rebreathing technique)
Time frame: 2-10 Days between exercise tests
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