Identifying Changes in Blood (Potential Biomarkers) in Individuals With Drug-Induced Liver Injury

University of North Carolina, Chapel Hill25 enrolled

Overview

The purpose of this study is to try to develop new blood tests that may help doctors identify if a drug is hurting a person's liver.

Our hypothesis is that there are liver-specific particles, called mRNA, that are identifiable in a person's blood sample during liver injury caused by some drugs. The purpose of this study is to try to develop new blood tests that may help doctors identify if a drug is hurting a person's liver, perhaps early in the process before significant injury or illness have occurred.

Study Type

OBSERVATIONAL

Enrollment

Conditions

Drug Induced Liver Injury

Eligibility

Sex: ALLMin age: 18 YearsMax age: 80 Years

Medical Language ↔ Plain English

Inclusion Criteria: * ALT \> 200 IU/L at presentation to UNC Hospitals * Drug induced liver injury considered likely by admitting medical staff

Locations (1)

University of North Carolina

Chapel Hill, North Carolina, United States

Data from ClinicalTrials.gov

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