Additive Effects of Pravastatin and Valsartan

Gachon University Gil Medical Center52 enrolled

Overview

The investigators hypothesize that pravastatin combined with valsartan may have additive effects in hypertensive, hypercholesterolemic patients.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

SINGLE

Enrollment

Conditions

Hypertension High Cholesterol

Interventions

pravastatin, valsartan, pravastatin+valsartanDRUG

pravastatin 40 mg, valsartan 160 mg 8 weeks of treatment

Eligibility

Sex: ALLMin age: 25 YearsMax age: 75 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Hypertension and low-density lipoprotein cholesterol levels \>100 Exclusion Criteria: * Overt liver disease Chronic renal failure Hypothyroidism Myopathy Uncontrolled diabetes Severe hypertension

Locations (1)

Gil Medical Center

Incheon, South Korea

Outcomes

Primary Outcomes

flow-mediated dilation

Time frame: 8 weeks of treatment

Secondary Outcomes

insulin resistance

Time frame: 8 weeks of treatment

Data from ClinicalTrials.gov

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