Probiotics and the Prevention of Traveler's Diarrhea

Inclusion Criteria: 1. Male and female subjects aged 18 or over. Upper age limit set by subject's ability to participate in the study; 2. Subject must give written informed consent; 3. Plan to travel to a geographic area with high risk of TD with a travel duration between 12 and 14 days; 4. Subjects must be willing to refrain from using anti-diarrheal medications or antibiotics during the study period, unless they become clinically indicated in which case a rescue regimen can be administered; 5. Subjects willing to refrain from eating yoghurt and taking other probiotics during the study; 6. Female subjects of child-bearing potential must agree to use adequate birth control during the study period. This will be defined as hormonal contraception or a double barrier-method. Exclusion Criteria: 1. Subjects who have been previously treated with PROTECFLOR® or who have participated in previous Lallemand-sponsored studies; 2. Subjects who have been born in a developing country. 3. Subjects with a history of substance or alcohol abuse or any other psychological condition that may, in the investigator's opinion, adversely affect their co-operation with the study; 4. Subjects who receive a cholera vaccine 5. Subjects with chronic diarrhea; 6. Subjects with chronic disease such as irritable bowel syndrome (IBS) or inflammatory bowel disease (IBD) or ulcerative colitis (UC) ; 7. Subjects with gastrointestinal (GI) surgery during the last 3 months; 8. Subjects who took systemic antibiotic 15 days or less prior to the study; 9. Subjects with immunodeficiency's or immune suppression; 10. Subjects being treated for cancer with radiotherapy and/or chemotherapy; 11. Subjects with organ transplants; 12. Subjects treated with immunosuppressant drugs; 13. Subjects receiving another probiotic preparations or having received probiotic preparations within the last 15 days; 14. Subjects with tube feeding, ileostomy and colostomy; 15. Subjects diagnosed Clostridium difficile colitis within the last 3 months; 16. Women who are pregnant, or who will not consent to using adequate birth control during the study period; 17. Women who are breastfeeding.