Exercise Training in Chagas Cardiomyopathy

Federal University of Minas Gerais37 enrolled

Overview

The benefits of exercise training in heart failure are well established. Its effects, however, have not been evaluated in Chagas cardiomyopathy (ChC). The investigators hypothesis is that the exercise training may improve functional capacity, quality of life (QoL), and reduce brain natriuretic peptide (BNP) levels in patients with ChC.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

NONE

Enrollment

Conditions

Chagas Disease Cardiomyopathy Exercise Training

Interventions

Exercise trainingOTHER

Eligibility

Sex: ALLMin age: 30 YearsMax age: 65 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Chronic Chagas dilated cardiomyopathy, defined by the echocardiography finding of a dilated left ventricle with moderate or severe impaired left ventricular systolic function (left ventricular ejection fraction ≤ 45%). * To be clinically stable for at least 3 months * To have sinus rhythm * To be under standard medical therapy use at the time. Exclusion Criteria: * Inability to attend regular exercise training * The presence of a pacemaker, associated cardiac or systemic diseases * Practitioners of regular physical activity

Locations (1)

Federal University of Minas Gerais

Belo Horizonte, Minas Gerais, Brazil

Outcomes

Primary Outcomes

Functional capacity

Time frame: 12 weeks

Functional class

Time frame: 12 weeks

Health related quality of life

Time frame: 12 weeks

BNP levels

Time frame: 12 weeks

Secondary Outcomes

Complications related to the exercise training

Time frame: 12 weeks

Data from ClinicalTrials.gov

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