Effects of Tea Catechin Consumption on the Prophylaxis of Influenza Infection

Masahiro Morikawa200 enrolled

Overview

The Purpose of this study is to evaluate the effects of 5 months catechin consumption on the prevention of influenza infection.

Catechins are the major components of tea flavonoids and are reported to possess physiological activities such as antiviral effects. Recent experimental studies have revealed that tea catechin extracts prevent influenza infection, but few studies have been conducted on the clinical effects of tea catechin consumption on the prophylaxis of influenza infection. Based on these backgrounds, we designed a prospective randomized controlled study to evaluate the effects of 5 months tea catechin consumption on the prophylaxis of influenza infection.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

PREVENTION

Masking

QUADRUPLE

Enrollment

200

Conditions

Influenza Infection

Interventions

tea catechin extractsDIETARY_SUPPLEMENT

Tea catechin extracts 540 mg/day, are consumed for 5 months.

Eligibility

Sex: ALLMin age: 20 YearsMax age: 90 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * aged over 20 years * possible to maintain without drinking tea more than 250 ml per day during the study * possible to maintain without taking supplements or herbal products including catechin extracts during the study * possible to fill out a questionnaire personally * Obtained written informed consent before participation Exclusion Criteria: * Possessing some chronic infectious diseases in need of therapy * Possessing tea or catechin allergy * Possessing a history of influenza infection before six months prior to the study * diagnosed as inadequate for other reasons to participate the study by principal investigator

Locations (1)

White Cross Nursing Home

Higashimurayama, Tokyo, Japan

Outcomes

Primary Outcomes

the incidence rates of influenza infection

Time frame: Until 5 months consumption of the study capsules

Secondary Outcomes

the incidence rates of upper respiratory tract infections

Time frame: Until 5 months consumption of the study capsules

the severity of the symptoms and the duration of the cold among incident cases

Time frame: Until 5 months consumption of the study capsules

occurrence of the adverse events

Time frame: Until 5 months consumption of the study capsules

Data from ClinicalTrials.gov

This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.