Study to Evaluate the Digestive Tolerability of ART44 Versus ART®50 in Patients With Osteoarthritis of the Knee

Inclusion Criteria: * Female or Male, aged 40 to 80 years, outpatient; * Presenting with internal femorotibial osteoarthritis: * Symptomatic for more than 6 months; * Meeting ACR clinical and radiological criteria; * Overall mean VAS score of knee pain in last 24 hours \> 40 mm (with no NSAIDs for over 72 hours and no analgesics for over 24 hours); * Pain present for at least one day out of 2 in the month preceding enrolment; * Radiological stage II to III (Kellgren and Lawrence) (image less than 12 months old). Exclusion Criteria: * Associated predominant symptomatic femoropatellar osteoarthritis; * Chondromatosis or villonodular synovitis of the knee; * Paget's Disease.