Study With Rituximab, Cyclophosphamide, Doxorubicin Liposomal (Myocet®), Vincristine, Prednisone, (R-COMP) to Treat Non-Hodgkin's Lymphoma

Inclusion Criteria: * NHL histological diagnosis of diffuse large B cell CD20 + (de novo or shift from low-grade NHL if not pretreated), grade IIIb follicular NHL; * Age \>= 18 years; * Presence of at least 1 factor that defines the cardiopathy; * Life expectancy \> 3 months; * In the case of women of childbearing age absence of pregnancy at the beginning of the chemotherapy; * Written informed consent. Exclusion Criteria: * Histology different from NHL diffuse large cell CD20 + or follicular IIIb * Age \< 18 years * Inability to sign informed consent; * HIV positivity; * Patients HBsAg positive; * AST/ALT \> 2 times the standard; * Bilirubin \> 2 times the standard; * Creatinine \> 2.5 mg / dl; * Location of CNS disease; * Pregnancy ongoing; * Damage to that organ or medical problems that could interfere with the therapy; * Current uncontrolled infection; * Senile dementia