The researchers will investigate gut microbiome in Korean patients with ulcerative colitis and normal control subjects using metagenomic analysis to elucidate the significant difference between two groups This study will help to understand the association between gut microbiome and inflammatory bowel disease.
Study Type
OBSERVATIONAL
Enrollment
15
Colonoscopy biopsy will be performed in rectum, ascending and descending colon at study entry
Stool will be collected from participants at study entry
colonoscopy biopsy will be conducted in rectum, ascending and descending colon from participants 2 times during study - at active phase and inactive phase
Seoul National University Hospital
Seoul, South Korea
RECRUITINGcharacterize the difference in gut microbiomes through metagenomic analysis between UC patients and normal control subjects
Time frame: 1 year
characterize the difference in gut microbiomes through metagenomic analysis between stool specimens and biopsy specimens in participants with UC and normal subjects
Time frame: 1 year
characterize the difference in gut microbiomes among colonoscopy biopsy locations (rectum, ascending and descending colon)
Time frame: 1 year
characterize the difference in gut microbiomes between active and inactive UC patients
Time frame: 1 year
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stool will be collected from participants 2 times during study - at active phase and inactive phase