Chronically total occlusions (CTO) are difficult to treat and have high risk for restenosis. Although everolimus-eluting stents (EES) \[(Xience, Abbott Vascular) or Promus (Boston Scientific)\] are very promising for the treatment of CTOs due to their low late loss and excellent deliverability, there are currently no published data on EES implantation in CTOs. The specific aim of this proposal is to examine the 8-month incidence of binary angiographic in-stent restenosis (defined as a stenosis of \> 50% of the minimum lumen diameter of the target stent) after implantation of the EES in CTO. It is the investigators hypothesis that EES-treated CTO lesions will have ≤ 20% 8-month in-stent binary angiographic restenosis rate.
Study Type
INTERVENTIONAL
Allocation
NA
Purpose
TREATMENT
Masking
NONE
Enrollment
100
everolimus-eluting stent (Xience, Abbott Vascular) or Promus (Boston Scientific)
Dallas VA Medical Center
Dallas, Texas, United States
In-stent binary angiographic restenosis rate
Time frame: 8 months
In-stent neointimal hyperplasia, as assessed by intravascular ultrasonography
Time frame: 8 months
Percent stent strut coverage, as assessed by optical coherence tomography
Time frame: 8 months
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