Detecting Early Myocardial Infiltration w/Amyloid & Light Chain Deposition Disease in Multiple Myeloma Subjects

University of Arkansas44 enrolled

Overview

The purpose of this study is to see if MRI techniques can be used for early evaluation of cardiac amyloidosis which is sometimes seen in individuals with multiple myeloma. Cardiac amyloidosis is a medical disorder that decreases heart function.

The purpose is to investigate the use of multiple newer CMR techniques for early evaluation of cardiac amyloidosis in multiple myeloma.

Study Type

OBSERVATIONAL

Enrollment

Conditions

Multiple Myeloma

Interventions

Administering three additional MRI imagesDEVICE

Three additional MRI images to determine the role of cardiac MR (CMR) in detecting features of early myocardial infiltration

Eligibility

Sex: ALLMin age: 18 YearsMax age: 80 Years

Medical Language ↔ Plain English

Inclusion Criteria: * All races and ethnic groups * Male and female ages 18-80 years of age * History of multiple myeloma * CMR study for evaluation for cardiac amyloidosis Exclusion Criteria: * Pregnant women * Subject with a metallic or electronic or other device that could be affected by the magnet

Locations (1)

University or Arkansas for Medical Sciences (UAMS)

Little Rock, Arkansas, United States

Outcomes

Primary Outcomes

This study is to see if MRI techniques can be used for early evaluation of cardiac amyloidosis which is sometimes seen in individuals with multiple myeloma.

Time frame: The time frame is five additional minutes & three additional images during and MRI.

Data from ClinicalTrials.gov

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