Analgetic Effect of Nitrousoxide-oxygen Inhalation for Dental Treatment of Children

University of Aarhus56 enrolled

Overview

To assess the analgetic effect of nitrousoxide-oxygen inhalation on pain perception in 12-15 years old children from 1) the dental pulp; 2) the masseter muscle; 3) the skin on the upper lip

The present study is a randomized, cross-over blinded study on the analgetic effect of nitrousoxide-oxygen on sensitivity of the dental pulp, the skin and muscles. It is conducted in healthy 12-15 year old Danish children attending public schools in the municipality of Aarhus, Denmark

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

TRIPLE

Enrollment

Conditions

Dental Pain Muscle Sensitivity to Pressure Skin Sensitivity to Electric Stimulation

Interventions

Nitrousoxide-oxygen and atmospheric airDRUG

Nitrousoxide-oxygen and atmospheric air

Atmospheric air; nitrousoxide-oxygenDRUG

Atmospheric air; nitrousoxide-oxygen

Eligibility

Sex: ALLMin age: 12 YearsMax age: 15 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * ASA-groups I or II * 12-15 year of age * sound upper central incisors Exclusion Criteria: * difficulties breathing through the nose * pregnancy * trauma to test teeth

Locations (1)

Dept. of Pediatric Dentistry, School of Dentistry, Faculty of Health Sciences, Aarhus University

Aarhus, Denmark

Outcomes

Primary Outcomes

Dental pain (pulp) threshold

Time frame: During and after inhalation

Secondary Outcomes

Muscle sensitivity to pressure

Time frame: During and after inhalation

Skin sensitivity ot electric stimulation

Time frame: During and after inhalation

Data from ClinicalTrials.gov

This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.