This study will investigate the Safety and Tolerability of Repeated Subcutaneous Injections of CAD106 in Alzheimer's Patients.
Study Type
INTERVENTIONAL
Allocation
NON_RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Enrollment
24
ATP Clinical Research, Inc.
Costa Mesa, California, United States
Alpin Research Center
Boulder, Colorado, United States
Sunrise Clinical Research, Inc.
Hollywood, Florida, United States
Alexian Brothers Neuroscience Institute
Elk Grove Village, Illinois, United States
Safety/tolerability assessments at multiple time points including but not limited to screening, and through to the end of the study to week 66.
Time frame: 66 weeks
Collect long-term safety information through SAE's collection for two years after completion of the extension study.
Time frame: 2 years
Immune response, cognitive and functional assessments at multiple time points including but not limited to baseline, and through to the end of the study to week 66.
Time frame: 66 weeks
Evaluate the antibody response after 4 additional injections in the Extension study, in patients initially treated with CAD106 in the Core study.
Time frame: 66 weeks
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Indiana University School of Medicine
Indianapolis, Indiana, United States
Drexel University College of Medicine
Philadelphia, Pennsylvania, United States
Volunteer Research Group
Knoxville, Tennessee, United States
University of Texas Southwestern
Dallas, Texas, United States