Safety of Phenylephrine Hydrochloride, Acetaminophen, Dimethindene Maleate Compared to Phenylephrine Hydrochloride Alone in Healthy Volunteers

Inclusion Criteria: * Healthy volunteers between 18 and 50 years; * Clinical examination without abnormal findings * Ability to understand the nature and purpose of the study, including the risks and adverse effects Exclusion Criteria: * Any cardiovascular disease, coronary artery disease, circulation problems or history of stroke, peripheral vascular disease or arrhythmia * History of serious adverse reactions or hypersensitivity any drug * Hypersensitivity to the drug study drugs or chemically related compounds