This is an observational, physiology pilot study of subjects with overactive bladder, insomnia and normal subjects. No study drug will be given. All subjects will complete a one week sleep diary and a 3-day bladder diary. After one week, subjects meeting eligibility requirements will complete a single sleep night stay in a sleep laboratory setting. During the sleep night stay, subjects will be evaluated using cystometry and polysomnography. In the morning following the sleep night stay, subjects will complete a sleep questionnaire and this will complete their participation in the study.
Study Type
OBSERVATIONAL
Enrollment
26
recording device measuring pressures though catheters placed in bladder and rectum
recording device measuring sleep activity through electrodes attached to the subject
Unnamed facility
Durham, North Carolina, United States
Number and proportion of voids associated with urgency
Time frame: During night in sleep lab
Number and proportion of voids associated with Detrusor Overactivity episodes within 10 minutes prior to the polysomnography (PSG) awakenings
Time frame: During night in sleep lab
Time from PSG awakening to each void in minutes
Time frame: During night in sleep lab
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