Cerebrovascular Autoregulation During Sepsis

Johannes Gutenberg University Mainz30 enrolled

Overview

The aim of the study is to correlate the dynamic cerebrovascular autoregulation by patients with sepsis with a sepsis-associated delirium.

Study Type

OBSERVATIONAL

Enrollment

Conditions

Sepsis Delirium

Interventions

no interventionsOTHER

No interventions

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: * clinical symptoms of sepsis, severe sepsis and septic shock * possibility for measurement of transcranial doppler ultrasound * age over 18 years Exclusion Criteria: * preexisting cerebrovascular disease * preexisting immunological disease * traumatic brain injury * intracranial infectious disease * pregnancy

Locations (1)

University medical centre Mainz

Mainz, Germany

Outcomes

Primary Outcomes

Disturbed cerebrovascular autoregulation correlates with sepsis associated delir

The Index of autoregulation (Mx) was measured and correlated with the clinical incidence of a sepsis associated delir

Time frame: 1 year

Secondary Outcomes

Correlation between inflammatory parameters and disturbed cerebrovascular autoregulation

Time frame: 1 year

Correlation between inflammatory parameters and sepsis-associated delirium

Time frame: 1 year

Data from ClinicalTrials.gov

This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.