Management of Index Episode in Patients With Bipolar Disorder Treated by Seroquel XR

Inclusion Criteria: * Patients eligible for entry into the study, male and females, will have a diagnosis of bipolar disorder, as defined by DSM-IV-TR and the current episode, whether it is manic, depressed or mixed will be treated with Seroquel XR since 1 week before entering the programme. * All eligible patients will be included in the programme provided they will receive information in advance and will sign consent to grant access to the data collected with regard to their condition during the observation interval proposed. Exclusion Criteria: * All the patients who have a known hypersensitivity to Seroquel XR/quetiapine or any of its excipients will not be included in this study. * Concomitant medication, that could result in drug interactions and could jeopardize patient safety will be carefully considered before having the patient enrolled. Additionally, all precautions applicable for special category patients will be taken into account, as detailed in current valid Romanian SmPC.